Effect of Aqueous Root Extract of Senna siamea Lam Reproductive Parameters of Male Wistar Rat <i>(Rattus norvegicus)</i>
Keywords:
morphometric, reproductive, root, Senna siamea, traditional medicineAbstract
Stress on animal considerably affects the relative efficiency by which body processes occur. The aim of this work is to study effects of aqueous root extract of Senna siamea on morphormetrics and some reproductive parameters using male wistar rats. Twenty weaned male wistar rats with average weight 86-97g were used for the study. The rats were randomly allotted based on their initial body weights (BW) into five (5) treatments (control; 0.25; 0.50; 0.75 and 1.00 ml/ kgBW) comprising six (6) rats. Feed and fresh water were given ad libitum. The aqueous extract was administered via oral route in the morning for ten (10) days consecutively. The results reveal that animals in the treated groups had better bodyweight and intestines than the control. The effect on sperm characteristics produced significant effect on mass motility, sperm concentration and abnormalities and insignificant effect on colour and mass activity in the treated rats compared to control. It is concluded that the extract is safe and beneficial if taken in safety dose. The results of this study justify the use of this plant as traditional medicine.
References
Amann, R. P. and Schanbacher, B. D. (1983). Physiology of male reproduction. Journal of Animal Science, 57, 380- 400.
Belibasaki, S. and Koulmtzis, S. (2000). Sexual activity and body testis growth in prepubertal ram lambs of Friesland, chios, kargouniki and serres dairy sheep in Greece. Small Ruminant Research, 37, 109- 113.
Cameron A. W. N., Fairnie I. J., Curnow D. I. I., Keogh E. H. and Lindsay D. R. (1984). The effect of frequency of semen collection and testicular size on the output of spermatozoa by ram. In proceeding of the 10th International Congress on Animal Reproduction Artificial Insemination. Vol II University of Illinois, u-c communication no 27.
Conco, W. Z. (1999). Zulu Traditional Medicine, its role in modern society. Community Health, 5, 8 – 13.
Cone E. J., Kalo K. and Hillsgrove M. (1996). Cocaine excretion in the semen of Drug users. Journal of Analytical Toxicology, 20 (2), 139- 140.
Duncan, D. B. (1955). Multiple Range and Multiple F Test. Biometrics 11, 1-42.
Edeoga, H. O., Okwu, D. E. and Mbaebie, B. O. (2005): Phytochemical constituents of some Nigerian Medicinal plants. African Journal of Biotechnology, 4(7), 685 – 688.
Fatehi, M., Rashidabady, T and Z. Fatehi-Hassanabad, Z. (2003): Effects of C. sativus petals extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea pig ileum. Journal of Ethnopharmacology, 84, 199-203.
Fatoba, T. A. and Ajigbogun, O. O. (2015). Effect of Aqueous root extract of Senna siamea Lam. on Physiological parameters of male wistar rats. Proceeding of the 49th Annual Conference of Agricultural Society of Nigeria (ASN), November 9th - 13th, 2015, Delta State University, Asaba Campus, Asaba, Delta State. pp 854-857.
Fowler, D. G. (2006): Traditional fever remedies: a list of Zambian plants. 1-61. Available online at http://www.giftshealth.org/ritam/news/Traditional.Fever.remedies1
Ganong, W. F. (2005). Review of Medical Physiology: International edition (twenty-second Edn.) Singapore: McGraw Hill Companies Inc, 25-557pp.
Hurd W. W., Kelly M. S., Ohl D. A., Ganvin J. M., Smith A. J. and Cummins, C. A. (1992). The effect of cocaine on sperm motility characteristics and bovine cervical mucus penetration. Fertilizer Sterilization, 57, 178 - 182.
Johnson B. H., Robinson O. W and Dillard E. U. (1974). Bodygrowth and testicular development in yearling Hereford bulls. Journal of Animal Science, 39, 213.
Karagiannidis A., Varsakeli S., Alexopoulos C. and Amarantidis I. (2000). Seasonal variation in semen characteristics of Chios and Friesian rams in Greece. Small Ruminant Research 37, 125-130.
Koolhaas J. M., Meerlo P., Boer S.F. D. et al., (1997). The temporal dynamics of the stress response. Neuroscience and Biobehavioral Reviews, 21, 775 – 782
Land, R. B. (1978). Reproduction in young sheep, some genetic and environment sources of variation. Jorunal of Reproductive Fertilizer, 52, 427-436.
Mbatchi S., Mbatchi B., Banzouzi J., Bansimba T. Nsonde N. G., Ouamba J., Berry A. and Benoit-Vical F. (2006). In vitro antiplasmodial activity of 18 plants used in Congo Brazzaville traditional medicine. Journal of Ethnopharmacology; 104, 168-174.
Notter D. R., Lucas J. R. and McClaugerty F. S. (1981). Accuracy of estimation of testis weight from in-situ testis mesures in ram lambs. Theriogenology 15:227-234.
Notter D. R., Lucas J. R., McClaugerty F. S. and Cpenhaver J. S. (1985). Breed group differences in testicular growth patterns in spring-born lambs. Journal of Animal Science, 60, 622-631.
Odason, E. E. and Kolawole, J. (2007) Anti-diabetic properties and brine shrimp toxicity of the aqueous extract of the root of Cassia siamea lam. (Ceasalpiniaceae). Nigerian Journal of Pharmaceutical Research, 6: 66-69.
Orwa C., Mutua A., Kindt R,. Jamnadass R. and Anthony S. (2009) Agroforestree Database: a tree reference and selection guide version 4.0. Available online at http:// www.worldagroforestry.org/sites/treedbs/treedatabases.asp
Osinwo, O. A. (2006). Introduction to Artificial Reproduction, 1st edition. Sophie Academic 31- 42pp.
Otimenyin S. O., Kolawole J. A. and Nwosu M. (2010): Pharmacological basis for the continual use of the root of Senna siamea in traditional medicine. International Journal of Pharma and Bio Sciences, 1(3), 1-9
Oyeyemi, M. O., Akusu, M. O. and Ola Davies, O. E. (2001). Effects of successive ejaculation on the spermiogram of West African Dwarf Goats. Israel Veterinary Medical Association, 56, 4.
Rahje T. A., Johnson R. K. and Lunstra B. D. (1995). Sperm production in boars after nine generations of selection for increased weight of testis. Journal of Animal Science, 77, 2177- 2185
Smith, O. B. and Somande, B. (1994). Interaction between nutrition and reproduction. In Farm Animal Proceedings January 17-21, 7-25pp.
Sutama, I. K. and Edey, T. N. (1985). Reproductive development during winter and spring of merino ram lambs growth at three different rates. Australian Journal of Agricultural Research, 36:461-467.
Trejo G. A., Ponce L.C. and Vidal G.M.A. (2000). Effects of melatonin and GnRH treatment on semen quality in young male Goats. 7th International conference on Goats, France 15-21, May 2000. 444-445pp.
