Pattern of Blood Pressure, Body Mass Index and Some Cardiac Enzymes in HIV Seropositive Patients in Sokoto, Nigeria

Abstract

HIV/AIDS infection is a global pandemic, and poses a serious health
challenge in sub-saharan Africa, Nigeria inclusive. Cardiac disease may
occur at any stage of HIV infection, but important manifestations are more
frequent with advanced immunodeficiency. Moreover, it has been reported
that complications from HIV infection includes arrhythmias, heart failure
myocardial infarction and coronary heart disease. The present study is
designed to investigate the pattern of blood pressure and some cardiac
enzymes in HIV seropositive subject in Sokoto metropolis Nigeria. A total of
one hundred and forty seropositive patients on HAART and HAART naïve
patients were investigated and compared with seventy seronegative controls.
HIV infection result into a lot of clinical manifestation cardiovascular
disorder inclusive. The result shows that CKMB and LDH were significantly
increase in patients on HAART as compared to those not on HAART, however,
there was also significant increased in systolic BP, Diastolic BP and body
mass index but not in total CK. When compared with control there is
significant increase in all the parameters in the study groups than in controls.
The study observes that there is need to monitor these parameters to prevent sudden cardiovascular complications in HIV seropositive patients.